Published in Journal of Industrial Engineering and Robotics, Volume 4, Number 4
Written by CÎRSTINA Maria-Mihaela, DECA Anca-Loredana, NEACȘU Alexandru-Ionuț
Scientific coordinators: Daniel GHICULESCU

The paper deals with the modeling and simulation of lab-on-a-chip microfluidic device is used for counting leukocytes in blood samples. Some aspects regarding the development stages of lab-on-a-chip devices are shown, which are extremely useful in the current pandemic conditions due to the rapidity of providing analysis results and the opportunity to perform certain determinations that are impossible using current conventional equipment. Comsol Multiphysics was used for finite element modeling and simulating device working, and for its geometric optimization. The velocities and the required travel time of the blood sample, the lysing and stop lysing substances, within two circuits are considered. These are formed by multiple coils with two counting channels of two cell types and a cells capture chamber. The conditions for the execution of the device were created on a millimeter silicon wafer using photochemical microtechnologies.

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